Higher coffee intake may be associated with significantly reduced cancer recurrence and death in patients with stage III colon cancer, according to a study of 953 patients with stage III colon cancer, during and 6 months after adjuvant chemotherapy. Researchers found that compared to patients who abstained from coffee:
*Patients consuming 4 or more cups of total coffee daily experienced an adjusted hazard ratio (HR) of 0.58 for recurrence or mortality.
*Patients consuming 4 or more cups of caffeinated coffee experienced significant reduced risk of recurrence or mortality (HR, 0.48).
*Increasing caffeine intake also conferred a significant reduction in recurrence or mortality (HR, 0.66).
Guercio BJ, Sato K, Niedzwiecki D, et al. Coffee intake, recurrence, and mortality in stage III colon cancer: results from CALGB 89803 (Alliance). J Clin Oncol. 2015 Aug 17